Aggrecan anticorps (Cleaved-Asp369)

N° du produit ABIN7220062

Détail du produit anti-Aggrecan anticorps

Antigène: Aggrecan (ACAN)

Épitope: AA 290-370, Cleaved-Asp369

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aggrecan est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Cleaved-Aggrecan (D369) Polyclonal Antibody

Specificité: Cleaved-Aggrecan (D369) Polyclonal Antibody detects endogenous levels of fragment of activated Aggrecan protein resulting from cleavage adjacent to D369.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human Aggrecan at AA range: 290-370

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Aggrecan

Antigène: Aggrecan (ACAN)

Autre désignation: Aggrecan (ACAN Produits)

Synonymes: anticorps AGC1, anticorps AGCAN, anticorps CSPG1, anticorps CSPGCP, anticorps MSK16, anticorps SEDK, anticorps Agc, anticorps Agc1, anticorps Cspg1, anticorps b2b183Clo, anticorps cmd, anticorps aggrecan, anticorps aggrecan core protein, anticorps ACAN, anticorps Acan, anticorps LOC100380783, anticorps AGC

Sujet: Rabbit Anti-Cleaved-Aggrecan (D369) Polyclonal Antibody,ACAN, AGC1, CSPG1, MSK16, Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1,ACAN is a member of the aggrecan/versican proteoglycan family. Aggrecan core protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.,Aggrecan core protein

Poids moléculaire: observerd band 44kDa

ID gène: 176

UniProt: P16112

Pathways: Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport