AMACR anticorps

N° du produit ABIN7201086

L’anticorps Souris Monoclonal anti-AMACR a été validé pour WB, IF et IHC (p). Il convient pour détecter AMACR dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AMACR anticorps (ABIN7201086)

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AMACR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-AMACR anticorps

Fonction: AMACR Monoclonal Antibody

Specificité: The antibody detects endogenous AMCAR/P504S proteins.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

Immunogène: Synthetic Peptide

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000), IF (1:200), IHC-P (1:200).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur AMACR

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Autre désignation: AMACR

Sujet: Mouse Anti-AMACR Monoclonal Antibody,AMACR, Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase,AMACR encodes a racemase. Alpha-methylacyl-CoA racemase interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Alpha-methylacyl-CoA racemase from this locus localize to both mitochondria and peroxisomes. Mutations in AMACR may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between AMACR and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.,Alpha-methylacyl-CoA racemase

ID gène: 23600

UniProt: Q9UHK6

Pathways: Monocarboxylic Acid Catabolic Process