Annexin VII anticorps (Internal Region)

N° du produit ABIN7218278

L’anticorps anti-Annexin VII Polyclonal Lapin est utilisé pour la détection de Annexin VII dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour Annexin VII anticorps (Internal Region) (ABIN7218278)

Antigène: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin VII est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Annexin VII anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-Annexin VII Polyclonal Antibody

Specificité: Annexin VII Polyclonal Antibody detects endogenous levels of Annexin VII protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Annexin VII

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Annexin VII

Antigène: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Autre désignation: Annexin VII

Sujet: ANXA7, ANX7, SNX, OK/SW-cl.95, Annexin A7, Annexin VII, Annexin-7, SynexinAnnexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2. and 2. kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.

Poids moléculaire: 53kD

ID gène: 310

UniProt: P20073