AATK anticorps (AA 1110-1190)
Aperçu rapide pour AATK anticorps (AA 1110-1190) (ABIN7229418)
Antigène
Voir toutes AATK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1110-1190
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Fonction
- Rabbit Anti-LMTK1 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of LMTK1 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human LMTK1 protein at AA range: 1110-1190
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- AATK (Apoptosis-Associated tyrosine Kinase (AATK))
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Autre désignation
- LMTK1
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Sujet
- Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BPThe protein encoded by AATK contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of AATK may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. AATK has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for AATK.
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Poids moléculaire
- 151kD
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ID gène
- 9625
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UniProt
- Q6ZMQ8
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Pathways
- Signalisation RTK, Regulation of Cell Size
Antigène
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