BIK anticorps (pSer35)

N° du produit ABIN7224186

Cet anticorps Lapin Polyclonal détecte spécifiquement BIK dans IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BIK anticorps (pSer35) (ABIN7224186)

Antigène: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIK est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-BIK anticorps

Épitope: pSer35

Fonction: Rabbit Anti-NBK (phospho Ser35) Polyclonal Antibody

Specificité: Phospho-NBK (S35) Polyclonal Antibody detects endogenous levels of NBK protein only when phosphorylated at S35.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human NBK Phospho-Ser35

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BIK

Antigène: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Autre désignation: NBK

Sujet: BIK, NBK, Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4The protein encoded by BIK (BCL2 interacting killer) shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

ID gène: 638

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity