Beclin 1 anticorps (AA 110-190)
Aperçu rapide pour Beclin 1 anticorps (AA 110-190) (ABIN7226846)
Antigène
Voir toutes Beclin 1 (BECN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 110-190
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Fonction
- Rabbit Anti-Beclin-1 Polyclonal Antibody
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Specificité
- Beclin-1 Polyclonal Antibody detects endogenous levels of Beclin-1.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from Beclin-1 at AA range: 110-190
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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Autre désignation
- Beclin-1
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Sujet
- Beclin 1, autophagy relatedBECN1 (beclin 1) encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 55kD
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ID gène
- 8678
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UniProt
- Q14457
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Pathways
- Autophagy
Antigène
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