BID anticorps (pSer78)

N° du produit ABIN7224182

Cet anticorps Lapin Polyclonal détecte spécifiquement BID dans IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour BID anticorps (pSer78) (ABIN7224182)

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BID est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-BID anticorps

Épitope: pSer78

Fonction: Rabbit Anti-BID (phospho Ser78) Polyclonal Antibody

Specificité: Phospho-BID (S78) Polyclonal Antibody detects endogenous levels of BID protein only when phosphorylated at S78.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human BID Phospho-Ser78

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BID

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Autre désignation: BID

Sujet: BID, BH3-interacting domain death agonist, p22 BID, BIDBID (BH3 interacting domain death agonist) encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

ID gène: 637

UniProt: P55957

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity