C1R anticorps (Cleaved-Arg463)

N° du produit ABIN7224738

Cet anticorps anti-C1R Polyclonal Lapin (ABIN7224738) détecte spécifiquement C1R dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour C1R anticorps (Cleaved-Arg463) (ABIN7224738)

Antigène: C1R (Complement Component 1, R Subcomponent (C1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1R est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-C1R anticorps

Épitope: AA 390-470, Cleaved-Arg463

Fonction: Rabbit Anti-Cleaved-C1r HC (R463) Polyclonal Antibody

Specificité: Cleaved-C1r HC (R463) Polyclonal Antibody detects endogenous levels of fragment of activated C1r HC protein resulting from cleavage adjacent to R463.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human C1r HC at AA range: 390-470

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur C1R

Antigène: C1R (Complement Component 1, R Subcomponent (C1R))

Autre désignation: C1r HC

Sujet: C1R, Complement C1r subcomponent, Complement component 1 subcomponent rThe first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full-length C1r chain and the cleaved B chain.

Poids moléculaire: 51kD

ID gène: 715

UniProt: P00736

Pathways: Système du Complément