Cadherin 5 anticorps

N° du produit ABIN7212382

Cet anticorps Souris Monoclonal détecte spécifiquement Cadherin 5 dans IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Cadherin 5 anticorps (ABIN7212382)

Antigène: Cadherin 5 (CDH5)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin 5 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 3G8

Détail du produit anti-Cadherin 5 anticorps

Fonction: Mouse Anti-VE-Cadherin Mouse Monoclonal Antibody (3G8)

Specificité: The antibody detects endogenous VE-Cadherin protein.

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic Peptide of VE-Cadherin

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: VE-Cadherin

Sujet: Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin, CD antigen CD144CDH5 (cadherin 5) encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. CDH5 is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.

Poids moléculaire: 80-115kD

ID gène: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2