Cadherin 7 anticorps (AA 620-700)

N° du produit ABIN7213912

L’anticorps anti-Cadherin 7 Polyclonal Lapin est utilisé pour la détection de Cadherin 7 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour Cadherin 7 anticorps (AA 620-700) (ABIN7213912)

Antigène: Cadherin 7 (CDH7)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Cadherin 7 anticorps

Épitope: AA 620-700

Fonction: Rabbit Anti-Cadherin-7 Polyclonal Antibody

Specificité: Cadherin-7 Polyclonal Antibody detects endogenous levels of Cadherin-7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human Cadherin-7 at AA range: 620-700

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cadherin 7

Antigène: Cadherin 7 (CDH7)

Autre désignation: Cadherin-7

Sujet: CDH7, CDH7L1, Cadherin-7CDH7 encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in CDH7 may be associated with bipolar disease in human patients. CDH7 is present in a gene cluster on chromosome 18.

Poids moléculaire: 87kD

ID gène: 1005

UniProt: Q9ULB5

Pathways: Cell-Cell Junction Organization