Caldesmon anticorps (pSer789)

N° du produit ABIN7213324

L’anticorps anti-Caldesmon Polyclonal Lapin est utilisé pour la détection de Caldesmon dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour Caldesmon anticorps (pSer789) (ABIN7213324)

Antigène: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caldesmon est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Caldesmon anticorps

Épitope: pSer789

Fonction: Caldesmon (phospho Ser789) Polyclonal Antibody

Specificité: Phospho-Caldesmon (S789) Polyclonal Antibody detects endogenous levels of Caldesmon protein only when phosphorylated at S789.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Caldesmon Phospho-Ser789

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Caldesmon

Antigène: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Autre désignation: Caldesmon

Sujet: Rabbit Anti-Caldesmon (phospho Ser789) Polyclonal Antibody,CALD1, CAD, CDM, Caldesmon, CDM,CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+)- dependent inhibition of smooth muscle contraction. Alternative splicing of CALD1 results in multiple transcript variants encoding distinct isoforms.,Caldesmon

Poids moléculaire: observerd band 80kDa

ID gène: 800

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction