Caldesmon anticorps
Aperçu rapide pour Caldesmon anticorps (ABIN7225122)
Antigène
Voir toutes Caldesmon (CALD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Caldesmon Polyclonal Antibody
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Specificité
- Caldesmon Polyclonal Antibody detects endogenous levels of Caldesmon protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human Caldesmon around the non-phosphorylation site of S759
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Autre désignation
- Caldesmon
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Sujet
- Rabbit Anti-Caldesmon Polyclonal Antibody,CALD1, CAD, CDM, Caldesmon, CDM,CALD1 (caldesmon 1) encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.,Caldesmon
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Poids moléculaire
- observerd band 93kDa
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ID gène
- 800
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UniProt
- Q05682
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Pathways
- Myometrial Relaxation and Contraction
Antigène
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