Cathepsin G anticorps (Cleaved-Ile21)
Aperçu rapide pour Cathepsin G anticorps (Cleaved-Ile21) (ABIN7212462)
Antigène
Voir toutes Cathepsin G (CTSG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 10-90, Cleaved-Ile21
-
Fonction
- Cleaved-Cathepsin G (I21) Polyclonal Antibody
-
Specificité
- Cleaved-Cathepsin G (I21) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin G protein resulting from cleavage adjacent to I21.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Immunogène
- Synthesized peptide derived from the N-terminal region of human Cathepsin G at AA range: 10-90
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
-
Commentaires
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Cathepsin G (CTSG)
-
Autre désignation
- Cathepsin G
-
Sujet
- Rabbit Anti-Cleaved-Cathepsin G (I21) Polyclonal Antibody,CTSG, Cathepsin G, CG,The protein encoded by CTSG, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease (cathepsin G) has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, cathepsin G is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this CTSG.,Cathepsin G
-
Poids moléculaire
- observerd band 29+36kDa
-
ID gène
- 1511
-
UniProt
- P08311
-
Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
Antigène
-