Cathepsin G anticorps (Cleaved-Ile21)

N° du produit ABIN7212462

L’anticorps anti-Cathepsin G Polyclonal Lapin est utilisé pour la détection de Cathepsin G dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour Cathepsin G anticorps (Cleaved-Ile21) (ABIN7212462)

Antigène: Cathepsin G (CTSG)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin G est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Cathepsin G anticorps

Épitope: AA 10-90, Cleaved-Ile21

Fonction: Rabbit Anti-Cleaved-Cathepsin G (I21) Polyclonal Antibody

Specificité: Cleaved-Cathepsin G (I21) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin G protein resulting from cleavage adjacent to I21.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human Cathepsin G at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cathepsin G

Antigène: Cathepsin G (CTSG)

Autre désignation: Cathepsin G

Sujet: CTSG, Cathepsin G, CGThe protein encoded by CTSG, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease (cathepsin G) has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, cathepsin G is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this CTSG.

Poids moléculaire: 28kD,26kD

ID gène: 1511

UniProt: P08311

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones