CDC25B anticorps (pSer353)

N° du produit ABIN7226168

Cet anticorps anti-CDC25B Polyclonal Lapin (ABIN7226168) détecte spécifiquement CDC25B dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Singe.

Aperçu rapide pour CDC25B anticorps (pSer353) (ABIN7226168)

Antigène: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CDC25B anticorps

Épitope: pSer353

Fonction: Cdc25B (phospho Ser353) Polyclonal Antibody

Specificité: Phospho-Cdc25B (S353) Polyclonal Antibody detects endogenous levels of Cdc25B protein only when phosphorylated at S353.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Cdc25B Phospho-Ser353

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CDC25B

Antigène: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Autre désignation: Cdc25B

Sujet: Rabbit Anti-Cdc25B (phospho Ser353) Polyclonal Antibody,CDC25B, CDC25HU2, M-phase inducer phosphatase 2, Dual specificity phosphatase Cdc25B,CDC25B (cell division cycle 25B) is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.,M-phase inducer phosphatase 2

Poids moléculaire: observerd band 64kDa

ID gène: 994

UniProt: P30305

Pathways: Cycle Cellulaire, M Phase, Autophagy