CERKL anticorps (AA 310-390)

N° du produit ABIN7214160

Cet anticorps Lapin Polyclonal détecte spécifiquement CERKL dans ELISA, WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CERKL anticorps (AA 310-390) (ABIN7214160)

Antigène: CERKL (Ceramide Kinase-Like (CERKL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CERKL est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CERKL anticorps

Épitope: AA 310-390

Fonction: Rabbit Anti-CERKL Polyclonal Antibody

Specificité: CERKL Polyclonal Antibody detects endogenous levels of CERKL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human CERKL at AA range: 310-390

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CERKL

Antigène: CERKL (Ceramide Kinase-Like (CERKL))

Autre désignation: CERKL

Sujet: CERKL, Ceramide kinase-like proteinCERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.

Poids moléculaire: 63kD

ID gène: 375298

UniProt: Q49MI3