CHAC1 anticorps

N° du produit ABIN7227870

Cet anticorps anti-CHAC1 Polyclonal Lapin (ABIN7227870) détecte spécifiquement CHAC1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour CHAC1 anticorps (ABIN7227870)

Antigène: CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHAC1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CHAC1 anticorps

Fonction: Rabbit Anti-CHAC1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CHAC1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CHAC1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CHAC1

Antigène: CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))

Autre désignation: CHAC1

Sujet: Glutathione-specific gamma-glutamylcyclotransferase 1, Gamma-GCG 1, Blocks Notch protein, Botch, Cation transport regulator-like protein 1CHAC1 encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of CHAC1 may indicate increased risk of cancer recurrence among breast and ovarian cancer patients.

Poids moléculaire: 24kD

ID gène: 79094

UniProt: Q9BUX1