Choline Acetyltransferase anticorps (Internal Region)
Aperçu rapide pour Choline Acetyltransferase anticorps (Internal Region) (ABIN7214194)
Antigène
Voir toutes Choline Acetyltransferase (CHAT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Internal Region
-
Fonction
- Choactase Polyclonal Antibody
-
Specificité
- Choactase Polyclonal Antibody detects endogenous levels of Choactase protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Immunogène
- Synthesized peptide derived from the Internal region of human Choactase
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
-
Commentaires
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
-
Autre désignation
- Choactase
-
Sujet
- Rabbit Anti-Choactase Polyclonal Antibody,CHAT, Choline O-acetyltransferase, CHOACTase, ChAT, Choline acetylase,CHAT encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. CHAT product (choline O-acetyltransferase) is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in CHAT have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in CHAT are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for CHAT, and some of these variants have been shown to encode more than one isoform.,Choline O-acetyltransferase
-
Poids moléculaire
- observerd band 82,7kDa
-
ID gène
- 1103
-
UniProt
- P28329
-
Pathways
- Skeletal Muscle Fiber Development
Antigène
-