CHD1L anticorps (Internal Region)

N° du produit ABIN7217606

L’anticorps anti-CHD1L Polyclonal Lapin est utilisé pour la détection de CHD1L dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour CHD1L anticorps (Internal Region) (ABIN7217606)

Antigène: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHD1L est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CHD1L anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-CHD1L Polyclonal Antibody

Specificité: CHD1L Polyclonal Antibody detects endogenous levels of CHD1L protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human CHD1L

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CHD1L

Antigène: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Autre désignation: CHD1L

Sujet: CHD1L, ALC1, Chromodomain-helicase-DNA-binding protein 1-like, Amplified in liver cancer protein 1CHD1L encodes a DNA helicase protein involved in DNA repair. The chromodomain-helicase-DNA-binding protein 1-like converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like) is a Protein Coding gene. Diseases associated with CHD1L include fibrosarcoma of bone. Among its related pathways are Chromatin Regulation / Acetylation and DNA Double-Strand Break Repair. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.

Poids moléculaire: 101kD

ID gène: 9557

UniProt: Q86WJ1