CDYL2 anticorps (AA 1-80)
Aperçu rapide pour CDYL2 anticorps (AA 1-80) (ABIN7214140)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-80
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Fonction
- Rabbit Anti-CDYL2 Polyclonal Antibody
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Specificité
- CDYL2 Polyclonal Antibody detects endogenous levels of CDYL2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the N-terminal region of human CDYL2 at AA range: 1-80
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ICC 1:200-1:1000,ELISA 1:20000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- CDYL2 (Chromodomain Protein, Y-Like 2 (CDYL2))
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Autre désignation
- CDYL2
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Sujet
- CDYL2, Chromodomain Y-like protein 2, CDY-like 2CDY, a gene family expressed exclusively in the testis, localizes to a region of the Y chromosome frequently deleted in infertile males. CDY protein contains two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and also a C-terminal domain which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY acts as a histone acetyltransferase, with strong preference for histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein (CDYL) is a related ubiquitous nuclear protein expressed at moderate levels in most tissues. The gene encoding for the CDYL protein localizes to chromosome 6p25.1.
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Poids moléculaire
- 56kD
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ID gène
- 124359
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UniProt
- Q8N8U2
Antigène
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