CNTF Receptor alpha anticorps

N° du produit ABIN7227986

L’anticorps anti-CNTF Receptor alpha Polyclonal Lapin est utilisé pour la détection de CNTF Receptor alpha dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour CNTF Receptor alpha anticorps (ABIN7227986)

Antigène: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTF Receptor alpha est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CNTF Receptor alpha anticorps

Fonction: Rabbit Anti-CNTFR Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CNTFR protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CNTFR protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CNTF Receptor alpha

Antigène: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Autre désignation: CNTFR

Sujet: Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alphaCNTFR encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in CNTFR may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for CNTFR.

Poids moléculaire: 40kD

ID gène: 1271

UniProt: P26992

Pathways: Signalistation JAK/STAT, Feeding Behaviour