Claudin 11 anticorps (AA 130-210)

N° du produit ABIN7222878

Cet anticorps anti-Claudin 11 est un anticorps Lapin Polyclonal détectant Claudin 11 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Claudin 11 anticorps (AA 130-210) (ABIN7222878)

Antigène: Claudin 11 (CLDN11)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 11 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Claudin 11 anticorps

Épitope: AA 130-210

Fonction: Claudin-11 Polyclonal Antibody

Specificité: Claudin-11 Polyclonal Antibody detects endogenous levels of Claudin-11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human Claudin-11 at AA range: 130-210

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Claudin 11

Antigène: Claudin 11 (CLDN11)

Autre désignation: Claudin-11

Sujet: Rabbit Anti-Claudin-11 Polyclonal Antibody,CLDN11, OSP, OTM, Claudin-11, Oligodendrocyte-specific protein,CLDN11 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by CLDN11 is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein claudin 11 is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.,Claudin-11

Poids moléculaire: observerd band 20kDa

ID gène: 5010

UniProt: O75508

Pathways: Hepatitis C