Claudin 19 anticorps (AA 50-130)

N° du produit ABIN7214214

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 19 dans WB et ELISA. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour Claudin 19 anticorps (AA 50-130) (ABIN7214214)

Antigène: Claudin 19 (CLDN19)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 19 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Claudin 19 anticorps

Épitope: AA 50-130

Fonction: Claudin-19 Polyclonal Antibody

Specificité: Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Claudin-19 at AA range: 50-130

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Claudin 19

Antigène: Claudin 19 (CLDN19)

Autre désignation: Claudin-19

Sujet: Rabbit Anti-Claudin-19 Polyclonal Antibody,CLDN19, Claudin-19,The product of CLDN19 belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in CLDN19 are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for CLDN19.,Claudin-19

Poids moléculaire: observerd band 23kDa

ID gène: 149461

UniProt: Q8N6F1

Pathways: Cell-Cell Junction Organization, Hepatitis C