CLP1 anticorps (AA 50-130)

N° du produit ABIN7227952

Cet anticorps Lapin Polyclonal détecte spécifiquement CLP1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CLP1 anticorps (AA 50-130) (ABIN7227952)

Antigène: CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CLP1 anticorps

Épitope: AA 50-130

Fonction: Rabbit Anti-CLP1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CLP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CLP1 protein at AA range: 50-130

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CLP1

Antigène: CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))

Autre désignation: CLP1

Sujet: Polyribonucleotide 5'-hydroxyl-kinase Clp1, Polyadenylation factor Clp1, Polynucleotide kinase Clp1, Pre-mRNA cleavage complex II protein Clp1CLP1 (Cleavage And Polyadenylation Factor I Subunit 1) encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in CLP1 are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for CLP1.

Poids moléculaire: 46kD

ID gène: 10978

UniProt: Q92989

Pathways: Ribonucleoprotein Complex Subunit Organization