Coagulation Factor IX anticorps (AA 412-461)
Aperçu rapide pour Coagulation Factor IX anticorps (AA 412-461) (ABIN7226924)
Antigène
Voir toutes Coagulation Factor IX (F9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 412-461
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Fonction
- Factor IX Polyclonal Antibody
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Specificité
- Factor IX Polyclonal Antibody detects endogenous levels of Factor IX.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from Factor IX at AA range: 412-461
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Coagulation Factor IX (F9)
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Autre désignation
- Factor IX
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Sujet
- Rabbit Anti-Factor IX Polyclonal Antibody,Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTC,F9(coagulation factor IX) encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of F9, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.,Factor IX
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Poids moléculaire
- observerd band 52kDa
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ID gène
- 2158
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UniProt
- P00740
Antigène
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