Coagulation Factor IX anticorps (AA 412-461)

N° du produit ABIN7226924

Cet anticorps anti-Coagulation Factor IX Polyclonal Lapin (ABIN7226924) détecte spécifiquement Coagulation Factor IX dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Coagulation Factor IX anticorps (AA 412-461) (ABIN7226924)

Antigène: Coagulation Factor IX (F9)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coagulation Factor IX est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Coagulation Factor IX anticorps

Épitope: AA 412-461

Fonction: Rabbit Anti-Factor IX Polyclonal Antibody

Specificité: Factor IX Polyclonal Antibody detects endogenous levels of Factor IX.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from Factor IX at AA range: 412-461

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Coagulation Factor IX

Antigène: Coagulation Factor IX (F9)

Autre désignation: Factor IX

Sujet: Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTCF9(coagulation factor IX) encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of F9, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

Poids moléculaire: 52kD

ID gène: 2158

UniProt: P00740