C8B anticorps (AA 371-420)

N° du produit ABIN7226914

Cet anticorps Lapin Polyclonal détecte spécifiquement C8B dans WB et ELISA. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour C8B anticorps (AA 371-420) (ABIN7226914)

Antigène: C8B (Complement Component 8, beta Polypeptide (C8B))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C8B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-C8B anticorps

Épitope: AA 371-420

Fonction: C8 β Polyclonal Antibody

Specificité: C8 β Polyclonal Antibody detects endogenous levels of C8 β.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from C8 beta at AA range: 371-420

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur C8B

Antigène: C8B (Complement Component 8, beta Polypeptide (C8B))

Autre désignation: C8 beta

Sujet: Rabbit Anti-C8 β Polyclonal Antibody,Complement component C8 beta chain, Complement component 8 subunit beta,C8B (complement C8 beta chain) encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.,C8 β

Poids moléculaire: observerd band 70kDa

ID gène: 732

UniProt: P07358

Pathways: Système du Complément