CNTNAP1 anticorps

N° du produit ABIN7227990

Cet anticorps Lapin Polyclonal détecte spécifiquement CNTNAP1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour CNTNAP1 anticorps (ABIN7227990)

Antigène: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTNAP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CNTNAP1 anticorps

Fonction: Rabbit Anti-CNTP1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CNTP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CNTP1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CNTNAP1

Antigène: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Autre désignation: CNTP1

Sujet: Contactin-associated protein 1, Caspr, Caspr1, Neurexin IV, Neurexin-4, p190CNTNAP1 product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for contactin-associated protein, includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Poids moléculaire: 152kD

ID gène: 8506

UniProt: P78357

Pathways: Cell-Cell Junction Organization