Cullin 7 anticorps (AA 1570-1650)

N° du produit ABIN7228102

L’anticorps anti-Cullin 7 Polyclonal Lapin est utilisé pour la détection de Cullin 7 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour Cullin 7 anticorps (AA 1570-1650) (ABIN7228102)

Antigène: Cullin 7 (CUL7)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 7 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Cullin 7 anticorps

Épitope: AA 1570-1650

Fonction: Rabbit Anti-CUL7 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CUL7 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CUL7 protein at AA range: 1570-1650

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cullin 7

Antigène: Cullin 7 (CUL7)

Autre désignation: CUL7

Sujet: Cullin-7, CUL-7The protein encoded by CUL7 (Cullin 7) is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in CUL7 are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for CUL7. CUL7 is a Protein Coding gene. Diseases associated with CUL7 include 3-M Syndrome 1 and 3-M Syndrome, Cul7-Related. Among its related pathways are Class I MHC mediated antigen processing and presentation and Unfolded Protein Response (UPR).

Poids moléculaire: 186kD

ID gène: 9820

UniProt: Q14999

Pathways: ER-Nucleus Signaling