Cyclin B3 anticorps

N° du produit ABIN7227656

L’anticorps anti-Cyclin B3 Polyclonal Lapin est utilisé pour la détection de Cyclin B3 dans des échantillons de Souris et Humain. Il a été validé pour ELISA et WB.

Aperçu rapide pour Cyclin B3 anticorps (ABIN7227656)

Antigène: Cyclin B3 (CCNB3)

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin B3 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-Cyclin B3 anticorps

Fonction: Rabbit Anti-CCNB3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CCNB3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CCNB3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cyclin B3

Antigène: Cyclin B3 (CCNB3)

Autre désignation: CCNB3

Sujet: G2/mitotic-specific cyclin-B3The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 153kD

ID gène: 85417

UniProt: Q8WWL7

Pathways: Cycle Cellulaire, Chromatin Binding