Cyclin E2 anticorps (pThr392)

N° du produit ABIN7225830

Cet anticorps anti-Cyclin E2 est un anticorps Lapin Polyclonal détectant Cyclin E2 dans IF et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour Cyclin E2 anticorps (pThr392) (ABIN7225830)

Antigène: Cyclin E2 (CCNE2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin E2 est non-conjugé

Application: Immunofluorescence (IF), ELISA

Détail du produit anti-Cyclin E2 anticorps

Épitope: pThr392

Fonction: Cyclin E2 (phospho Thr392) Polyclonal Antibody

Specificité: Phospho-Cyclin E2 (T392) Polyclonal Antibody detects endogenous levels of Cyclin E2 protein only when phosphorylated at T392.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Cyclin E2 Phospho-Thr392

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Cyclin E2

Antigène: Cyclin E2 (CCNE2)

Autre désignation: Cyclin E2

Sujet: Rabbit Anti-Cyclin E2 (phospho Thr392) Polyclonal Antibody,CCNE2, G1/S-specific cyclin-E2,The protein encoded by CCNE2 (cyclin E2)belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of CCNE2 peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.,G1

ID gène: 9134

UniProt: O96020

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases