Cyclin T1 anticorps (AA 220-300)

N° du produit ABIN7227666

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin T1 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Cyclin T1 anticorps (AA 220-300) (ABIN7227666)

Antigène: Cyclin T1 (CCNT1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin T1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Cyclin T1 anticorps

Épitope: AA 220-300

Fonction: CCNT1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CCNT1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human CCNT1 protein at AA range: 220-300

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Cyclin T1

Antigène: Cyclin T1 (CCNT1)

Autre désignation: CCNT1

Sujet: Rabbit Anti-CCNT1 Polyclonal Antibody,Cyclin-T1, CycT1, Cyclin-T,CCNT1 (Cyclin T1) encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of CCNT1 is implicated in tumor growth. Alternative splicing results in multiple transcript variants.,CCNT1

Poids moléculaire: observerd band 79kDa

ID gène: 904

UniProt: O60563