CYB5R3 anticorps (AA 110-190)
Aperçu rapide pour CYB5R3 anticorps (AA 110-190) (ABIN7214388)
Antigène
Voir toutes CYB5R3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 110-190
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Fonction
- Rabbit Anti-CYB5R3 Polyclonal Antibody
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Specificité
- CYB5R3 Polyclonal Antibody detects endogenous levels of CYB5R3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the Internal region of human CYB5R3 at AA range: 110-190
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))
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Autre désignation
- CYB5R3
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Sujet
- CYB5R3, DIA1, NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, Diaphorase-1CYB5R3 encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in CYB5R3 cause methemoglobinemias.
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Poids moléculaire
- 34kD
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ID gène
- 1727
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UniProt
- P00387
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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