COX10 anticorps (Internal Region)

N° du produit ABIN7219600

L’anticorps anti-COX10 Polyclonal Lapin est utilisé pour la détection de COX10 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour COX10 anticorps (Internal Region) (ABIN7219600)

Antigène: COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX10 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-COX10 anticorps

Épitope: Internal Region

Fonction: COX10 Polyclonal Antibody

Specificité: COX10 Polyclonal Antibody detects endogenous levels of COX10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human COX10

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur COX10

Antigène: COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

Autre désignation: COX10

Sujet: Rabbit Anti-COX10 Polyclonal Antibody,COX10, Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase,Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. COX10 encodes heme A: farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. COX10, heme A: farnesyltransferase cytochrome c oxidase assembly factor is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.,Protoheme IX farnesyltransferase mitochondrial

Poids moléculaire: observerd band 49kDa

ID gène: 1352

UniProt: Q12887