CRLF3 anticorps (AA 270-350)

N° du produit ABIN7228062

Cet anticorps anti-CRLF3 Polyclonal Lapin (ABIN7228062) détecte spécifiquement CRLF3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CRLF3 anticorps (AA 270-350) (ABIN7228062)

Antigène: CRLF3 (Cytokine Receptor-Like Factor 3 (CRLF3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRLF3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CRLF3 anticorps

Épitope: AA 270-350

Fonction: Rabbit Anti-CRLF3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CRLF3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CRLF3 protein at AA range: 270-350

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CRLF3

Antigène: CRLF3 (Cytokine Receptor-Like Factor 3 (CRLF3))

Autre désignation: CRLF3

Sujet: Cytokine receptor-like molecule 9, CREME-9, Cytokine receptor-related protein 4, Type I cytokine receptor-like factor p48CRLF3 (Cytokine Receptor Like Factor 3) is a Protein Coding gene. CRLF3 encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. CRLF3 is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing ofCRLF3 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.

Poids moléculaire: 48kD

ID gène: 51379

UniProt: Q8IUI8

Pathways: Signalisation p53