DDB2 anticorps (AA 260-340)

N° du produit ABIN7228156

L’anticorps Lapin Polyclonal anti-DDB2 a été validé pour WB et ELISA. Il convient pour détecter DDB2 dans des échantillons de Humain et Souris.

Aperçu rapide pour DDB2 anticorps (AA 260-340) (ABIN7228156)

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DDB2 anticorps

Épitope: AA 260-340

Fonction: DDB2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of DDB2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human DDB2 protein at AA range: 260-340

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur DDB2

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Autre désignation: DDB2

Sujet: Rabbit Anti-DDB2 Polyclonal Antibody,DNA damage-binding protein 2, DDB p48 subunit, DDBb, Damage-specific DNA-binding protein 2, UV-damaged DNA-binding protein 2, UV-DDB 2,DDB2 encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.,DDB2

Poids moléculaire: observerd band 46kDa

ID gène: 1643

UniProt: Q92466

Pathways: Réparation de l'ADN