Desmoglein 2 anticorps (AA 370-450)

N° du produit ABIN7220094

Cet anticorps Lapin Polyclonal détecte spécifiquement Desmoglein 2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Desmoglein 2 anticorps (AA 370-450) (ABIN7220094)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Desmoglein 2 anticorps

Épitope: AA 370-450

Fonction: Rabbit Anti-Dsg2 Polyclonal Antibody

Specificité: Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Dsg2 at AA range: 370-450

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: Dsg2

Sujet: DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGCDSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Poids moléculaire: 140kD

ID gène: 1829

UniProt: Q14126

Pathways: Cell-Cell Junction Organization