DAAM1 anticorps (AA 400-500)

N° du produit ABIN7228144

Cet anticorps anti-DAAM1 Polyclonal Lapin (ABIN7228144) détecte spécifiquement DAAM1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour DAAM1 anticorps (AA 400-500) (ABIN7228144)

Antigène: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAAM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DAAM1 anticorps

Épitope: AA 400-500

Fonction: Rabbit Anti-DAAM1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of DAAM1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human DAAM1 protein at AA range: 400-500

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DAAM1

Antigène: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Autre désignation: DAAM1

Sujet: Disheveled-associated activator of morphogenesis 1Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by DAAM1 contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by DAAM1 is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Poids moléculaire: 123kD

ID gène: 23002

UniProt: Q9Y4D1

Pathways: Signalisation WNT