DCLRE1C anticorps (pSer516)

N° du produit ABIN7224264

L’anticorps anti-DCLRE1C Polyclonal produit chez le Lapin a été validé pour WB, ELISA et IHC (p). Il convient pour la détection de DCLRE1C dans des échantillons provenant de Humain et Souris. }

Aperçu rapide pour DCLRE1C anticorps (pSer516) (ABIN7224264)

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLRE1C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DCLRE1C anticorps

Épitope: pSer516

Fonction: Artemis (phospho Ser516) Polyclonal Antibody

Specificité: Phospho-Artemis (S516) Polyclonal Antibody detects endogenous levels of Artemis protein only when phosphorylated at S516.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Artemis Phospho-Ser516

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur DCLRE1C

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Autre désignation: Artemis

Sujet: Rabbit Anti-Artemis (phospho Ser516) Polyclonal Antibody,DCLRE1C, ARTEMIS, ASCID, SCIDA, SNM1C, Protein artemis, DNA cross-link repair 1C protein, Protein A-SCID, SNM1 homolog C, hSNM1C, SNM1-like protein,DCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.,Protein artemis

ID gène: 64421

UniProt: Q96SD1

Pathways: Réparation de l'ADN