DOT1L anticorps (AA 700-780)

N° du produit ABIN7228274

Cet anticorps Lapin Polyclonal détecte spécifiquement DOT1L dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DOT1L anticorps (AA 700-780) (ABIN7228274)

Antigène: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOT1L est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DOT1L anticorps

Épitope: AA 700-780

Fonction: Rabbit Anti-DOT1L Polyclonal Antibody

Specificité: The antibody detects endogenous levels of DOT1L protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human DOT1L protein at AA range: 700-780

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DOT1L

Antigène: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Autre désignation: DOT1L

Sujet: Histone-lysine N-methyltransferase, H3 lysine-79 specific, DOT1-like protein, Histone H3-K79 methyltransferase, H3-K79-HMTase, Lysine N-methyltransferase 4DOT1L encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. DOT1L (DOT1 Like Histone Lysine Methyltransferase) is a Protein Coding gene. Diseases associated with DOT1L include Diffuse Gastric Cancer and Leukemia, Acute Myeloid. Among its related pathways are Chromatin organization and Transcriptional misregulation in cancer.

Poids moléculaire: 191kD

ID gène: 84444

UniProt: Q8TEK3