Dysferlin anticorps (AA 1950-2030)

N° du produit ABIN7225232

Cet anticorps anti-Dysferlin est un anticorps Lapin Polyclonal détectant Dysferlin dans WB, ELISA et IF. Adapté pour Humain et Souris.

Aperçu rapide pour Dysferlin anticorps (AA 1950-2030) (ABIN7225232)

Antigène: Dysferlin (DYSF)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dysferlin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-Dysferlin anticorps

Épitope: AA 1950-2030

Fonction: Dysferlin Polyclonal Antibody

Specificité: Dysferlin Polyclonal Antibody detects endogenous levels of Dysferlin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human Dysferlin at AA range: 1950-2030

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Dysferlin

Antigène: Dysferlin (DYSF)

Autre désignation: Dysferlin

Sujet: Rabbit Anti-Dysferlin Polyclonal Antibody,DYSF, FER1L1, Dysferlin, Dystrophy-associated fer-1-like protein, Fer-1-like protein 1,The protein encoded by DYSF (dysferlin) belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by DYSF binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in DYSF have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.,Dysferlin

Poids moléculaire: observerd band 240kDa

ID gène: 8291

UniProt: O75923