Dystroglycan anticorps (AA 830-910)
Aperçu rapide pour Dystroglycan anticorps (AA 830-910) (ABIN7228146)
Antigène
Voir toutes Dystroglycan (DAG1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 830-910
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Fonction
- DAG1 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of DAG1 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human DAG1 protein at AA range: 830-910
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))
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Autre désignation
- DAG1
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Sujet
- Rabbit Anti-DAG1 Polyclonal Antibody,Dystroglycan, Dystrophin-associated glycoprotein 1, Alpha-dystroglycan, Alpha-DG, Beta-DG,DAG1 encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.,DAG1
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Poids moléculaire
- observerd band 98kDa
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ID gène
- 1605
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UniProt
- Q14118
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Pathways
- Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
Antigène
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