RAD18 anticorps (AA 270-350)
Aperçu rapide pour RAD18 anticorps (AA 270-350) (ABIN7216744)
Antigène
Voir toutes RAD18 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 270-350
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Fonction
- Rad18 Polyclonal Antibody
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Specificité
- Rad18 Polyclonal Antibody detects endogenous levels of Rad18 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human Rad18 at AA range: 270-350
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
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Autre désignation
- Rad18
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Sujet
- Rabbit Anti-Rad18 Polyclonal Antibody,RAD18, RNF73, E3 ubiquitin-protein ligase RAD18, Postreplication repair protein RAD18, hHR18, hRAD18, RING finger protein 73,RAD18, E3 ubiquitin protein ligase encoded by RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18, E3 ubiquitin protein ligase is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.,E3 ubiquitin-protein ligase RAD18
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Poids moléculaire
- observerd band 56kDa
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ID gène
- 56852
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UniProt
- Q9NS91
Antigène
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