EDAR anticorps (AA 50-130)

N° du produit ABIN7228346

Cet anticorps Lapin Polyclonal détecte spécifiquement EDAR dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour EDAR anticorps (AA 50-130) (ABIN7228346)

Antigène: EDAR (Ectodysplasin A Receptor (EDAR))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDAR est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EDAR anticorps

Épitope: AA 50-130

Fonction: Rabbit Anti-EDAR Polyclonal Antibody

Specificité: The antibody detects endogenous levels of EDAR protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human EDAR protein at AA range: 50-130

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur EDAR

Antigène: EDAR (Ectodysplasin A Receptor (EDAR))

Autre désignation: EDAR

Sujet: Tumor necrosis factor receptor superfamily member EDAR, Anhidrotic ectodysplasin receptor 1, Downless homolog, EDA-A1 receptor, Ectodermal dysplasia receptor, Ectodysplasin-A receptorEDAR encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Poids moléculaire: 49kD

ID gène: 10913

UniProt: Q9UNE0

Pathways: Tube Formation, Ubiquitin Proteasome Pathway