Elastin anticorps

N° du produit ABIN7228384

Cet anticorps anti-Elastin est un anticorps Lapin Polyclonal détectant Elastin dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour Elastin anticorps (ABIN7228384)

Antigène: Elastin (ELN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Elastin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Elastin anticorps

Fonction: ELN Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ELN protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human ELN protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Elastin

Antigène: Elastin (ELN)

Autre désignation: ELN

Sujet: Rabbit Anti-ELN Polyclonal Antibody,Elastin, Tropoelastin,ELN gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa.,ELN

Poids moléculaire: observerd band 86kDa

ID gène: 2006

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization