NEIL2 anticorps

N° du produit ABIN7229952

L’anticorps Lapin Polyclonal anti-NEIL2 a été validé pour WB et ELISA. Il convient pour détecter NEIL2 dans des échantillons de Humain et Souris.

Aperçu rapide pour NEIL2 anticorps (ABIN7229952)

Antigène: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEIL2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NEIL2 anticorps

Fonction: NEIL2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of NEIL2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human NEIL2 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur NEIL2

Antigène: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Autre désignation: NEIL2

Sujet: Rabbit Anti-NEIL2 Polyclonal Antibody,Endonuclease 8-like 2, DNA glycosylase/AP lyase Neil2, DNA-(apurinic or apyrimidinic site) lyase Neil2, Endonuclease VIII-like 2, Nei homolog 2, NEH2, Nei-like protein 2,NEIL2 encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified.,NEIL2

Poids moléculaire: observerd band 36kDa

ID gène: 252969

UniProt: Q969S2

Pathways: Réparation de l'ADN