Endothelin 1 anticorps (Internal Region)
Aperçu rapide pour Endothelin 1 anticorps (Internal Region) (ABIN7217844)
Antigène
Voir toutes Endothelin 1 (EDN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Internal Region
-
Fonction
- ET-1 Polyclonal Antibody
-
Specificité
- ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Immunogène
- Synthesized peptide derived from the Internal region of human ET-1
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
-
Commentaires
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Endothelin 1 (EDN1)
-
Autre désignation
- ET-1
-
Sujet
- Rabbit Anti-ET-1 Polyclonal Antibody,EDN1, Endothelin-1, Preproendothelin-1, PPET1,EDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.,Endothelin-1
-
Poids moléculaire
- observerd band 25kDa
-
ID gène
- 1906
-
UniProt
- P05305
-
Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
Antigène
-