ECE2 anticorps
Aperçu rapide pour ECE2 anticorps (ABIN7228344)
Antigène
Voir toutes ECE2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit Anti-ECE2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of ECE2 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human ECE2 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- ECE2 (Endothelin Converting Enzyme 2 (ECE2))
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Autre désignation
- ECE2
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Sujet
- Endothelin-converting enzyme 2ECE2 (Endothelin Converting Enzyme 2) is a Protein Coding gene. Among its related pathways are A-beta Pathways: uptake and Degradation and Peptide ligand-binding receptors. GO annotations related to this gene include methyltransferase activity and metalloendopeptidase activity. An important paralog of this gene is ECE1. Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
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Poids moléculaire
- 97kD
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ID gène
- 9718
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UniProt
- O60344
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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