ERBB2IP anticorps (pTyr1104)

N° du produit ABIN7212952

Cet anticorps anti-ERBB2IP Polyclonal Lapin (ABIN7212952) détecte spécifiquement ERBB2IP dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ERBB2IP anticorps (pTyr1104) (ABIN7212952)

Antigène: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERBB2IP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ERBB2IP anticorps

Épitope: pTyr1104

Fonction: Rabbit Anti-Erbin (phospho Tyr1104) Polyclonal Antibody

Specificité: Phospho-Erbin (Y1104) Polyclonal Antibody detects endogenous levels of Erbin protein only when phosphorylated at Y1104.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Erbin Phospho-Tyr1104

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ERBB2IP

Antigène: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Autre désignation: Erbin

Sujet: ERBB2IP, ERBIN, KIAA1225, LAP2, Protein LAP2, Densin-180-like protein, Erbb2-interacting protein, ErbinERBIN is a member of the leucine-rich repeat and PDZ domain (LAP) family.Erbb2 interacting protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ERBIN.

Poids moléculaire: 172kD

ID gène: 55914

UniProt: Q96RT1

Pathways: EGFR Signaling Pathway, Asymmetric Protein Localization