ERI1 anticorps (AA 230-310)

N° du produit ABIN7225780

Cet anticorps anti-ERI1 est un anticorps Lapin Polyclonal détectant ERI1 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ERI1 anticorps (AA 230-310) (ABIN7225780)

Antigène: ERI1 (Exoribonuclease 1 (ERI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ERI1 anticorps

Épitope: AA 230-310

Fonction: ERI1 Polyclonal Antibody

Specificité: ERI1 Polyclonal Antibody detects endogenous levels of ERI1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human ERI1 at AA range: 230-310

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur ERI1

Antigène: ERI1 (Exoribonuclease 1 (ERI1))

Autre désignation: ERI1

Sujet: Rabbit Anti-ERI1 Polyclonal Antibody,ERI1, 3'EXO, THEX1, 3'-5' exoribonuclease 1, 3'-5' exonuclease ERI1, Eri-1 homolog, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo, HEXO,ERI1, also named as HEXO, 3'HEXO and THEX1, contains one exonuclease domain and one SAP domain. The SAP domain is necessary for binding to the stem-loop structure of histone mRNAs and to form the ternary complex with SLBP, but not for 3'-end histone mRNA exonuclease activity. It is a RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is able to bind other mRNAs. ERI1 is required for 5. S rRNA 3'-end processing. It also binds to 5. s ribosomal RNA. ERI1 binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.,3'-5' exoribonuclease 1

Poids moléculaire: observerd band 37kDa

ID gène: 90459

UniProt: Q8IV48